The film tells a story about a spoiled Beverly Hills female Chihuahua dog, who accidentally finds herself lost in Mexico and must rely on some new friends, including a street-hardened German Shepherd and an amorous pup, on her incredible journey back home.
Dreamworks/Paramount's thriller "Eagle Eye" had minimum drop-off in its second week of release, and was in second place with 17.7 million dollars over the weekend, according to Los Angeles-based box office tracking firm Media By Numbers.
"Nick And Norah's Infinite Playlist," a comedy drama from Sony Pictures about two teenagers ends up their first date while going on an all-night quest to find their favorite rock band's secret show, enjoyed the next-best opening after "Chihuahua," was on track to take in 13 million dollars, good enough to open in third place.
Warner Bros.' middle-age love story "Nights in Rodanthe" was in fourth place, taking in 7.4 million dollars over the three-day period in its second weekend of release, followed by western "Appaloosa" from the same studio with 5 million dollars.



